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神经-内分泌对免疫功能的调节,免疫系统对中枢神经内分泌的反馈作用,组成十分复杂的调节环路.阿片肽参与对免疫功能的调节,不同实验室报告结果不尽一致,特别是阿片肽对影响动物淋巴细胞丝裂原反应方面,有些实验显示增强作用,有的则是相反的结果,为此,作者选用不同浓度β-内啡肽(β-endorph-in.β-END)在控制同样的实验条件下,研究它对BALB/C小鼠和SD大鼠脾淋巴细胞的PHA反应的影响,探索不同动物种属.在神经内分泌对免疫反应调节中的特点.
Nervous-endocrine regulation of immune function, the immune system on the central nervous system endocrine feedback, the composition of a very complex regulatory loop opioid peptide involved in the regulation of immune function, different laboratories reported results are not consistent, especially opioid peptide pairs Some experiments showed enhancement effect on the mitogen reaction of animal lymphocytes, while others were the opposite results. Therefore, the authors chose different concentrations of β-endorph-in.β-END to control the same Under the experimental conditions, to study its effects on the PHA response of splenic lymphocytes of BALB / C mice and SD rats and explore the characteristics of different animal species in the regulation of neuroendocrine immune response.