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目的:探究分析西咪替丁联合奥美拉唑在应激性胃溃疡治疗中的临床效果。方法:选取2014年3月至2016年6月武警西藏边防部队官兵中患有应激性胃溃疡患者66例作为本次研究对象,采用数字随机分配法将这些患者分为实验组和对照组,每组共有患者33例。实验组采用西咪替丁联合奥美拉唑治疗,对照组单纯的采用西咪替丁治疗,对两组患者的临床治疗效果进行分析比较。结果:实验组患者总有效率为96.97%,对照组患者总有效率为66.67%,实验组总有效率明显高于对照组,且实验组患者血清胃泌素水平及止血时间均明显低于对照组,P<0.05,差异具有统计学意义。结论:对应激性胃溃疡患者采取西咪替丁联合奥美拉唑治疗能够降低患者血清胃泌素水平、调节患者胃内环境、缩短患者止血时间,对患者的溃疡创面愈合有良好的治疗效果,值得临床推广使用。
Objective: To investigate the clinical effect of cimetidine combined with omeprazole in the treatment of stress ulcer. Methods: From March 2014 to June 2016, 66 Armed Police Corps soldiers suffering from stress ulcer were selected as the subjects of this study. The patients were divided into experimental group and control group by digital random distribution method. A total of 33 patients in each group. The experimental group was treated with cimetidine combined with omeprazole, while the control group was treated with cimetidine only. The clinical effects of the two groups were analyzed and compared. Results: The total effective rate was 96.97% in the experimental group and 66.67% in the control group. The total effective rate in the experimental group was significantly higher than that in the control group, and the serum gastrin level and bleeding time in the experimental group were significantly lower than those in the control group Group, P <0.05, the difference was statistically significant. Conclusion: The treatment of stress ulcer patients with cimetidine combined with omeprazole can reduce serum gastrin levels, regulate the patient’s stomach environment, shorten the time to stop bleeding in patients with ulcer wound healing have a good therapeutic effect , It is worth to promote clinical use.