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目的观察喉罩在乳癌改良根治术中应用的安全性和可行性。方法选择ASAⅠ~Ⅱ级乳癌改良根治手术患者80例,随机分为两组,每组40例。Ⅰ组为喉罩置入全麻,Ⅱ组为气管内插管全麻,记录麻醉前5min及置入喉罩或者气管内插管即刻的心率(HR)、收缩压(SBP)及舒张压(DBP),同时记录术中及术后并发症发生的例数。结果Ⅰ组插入喉罩前后HR、SBP及DBP无显著改变,而Ⅱ组插管后HR增快、SBP及DBP均增高(P<0.05);Ⅱ组并发症的发生率显著高于Ⅰ组(P<0.05)。结论喉罩全身麻醉血流动力学平稳,在择期手术中是一种安全、有效、容易使用的声门上通气装置,可替代气管插管用于乳癌改良根治术。“,”Aim To observe the safety and feasibility of laryngeal mask airway in modified radical mastectomy. Methods 80 patients,ASA I~Ⅱ,undergoing modified radical mastectomy,were randomly divided into 2 groups(n=40). Group I received general anesthesia with laryngeal mask airway,and group II received general anesthesia with intratracheal intubation.Observe the HR and SBP and DBP of all patients at 5 min before anesthesia and immesiately after laryngeal mask airway insertion or intratracheal intubation.The intraoperative and postoperative complications were also documented. Results There was no significant change of HR,SBP and DBP during laryngeal mask airway insertion for group I,while HR and SBP and DBP all increased after intubation for group II(P<0.05).The incidence of complications was also higher in group II(P<0.05).Conclusions Laryngeal mask airway can maintain a stable hemodynamics,and it was a safe and effective and easily-using supraglottic airway in elective surgery,so it can replace intratracheal intubation in modified radical mastectomy.