HMGI C属于高迁移率蛋白I家族 ,是一种含有多种蛋白激酶作用位点的染色体结合蛋白。它和同家族的HMGI/Y基因来源不同 ,但结构和功能很相似。在结构上 ,它保留了代表该家族蛋白特征的三个碱性DNA结合结构域。在功能上 ,HMGI C基因与控制胚胎期细胞的生长和肿瘤细胞转化有关 ,其生物学行为类似癌基因 ,是一种潜在的肿瘤标记。 HMGI C belongs to the high mobility protein I family and is a chromosome-binding protein containing multiple protein kinases. It is not the same source as the HMGI/Y gene in the same family, but its structure and function are similar. Structurally, it retains three basic DNA binding domains that characterize the proteins of this family. Functionally, HMGI C gene is involved in controlling the growth of embryonic cells and the transformation of tumor cells. Its biological behavior is similar to that of oncogene and is a potential tumor marker.