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作者对光照疗法（光疗）前及光疗后于口服维生素Ｂ＿２（４３例）和不予口服维生素Ｂ＿２（１７例）的黄疸新生儿的红细胞谷胱甘肽还原酶（ＧＲ）的活性进行了动态观察。结果显示，接受短期光疗的黄疸新生儿其红细胞ＧＲ活性较光疗前的ＧＲ活性有显著下降，光疗后予口服维生素Ｂ＿２可使下降的红细胞ＧＲ活性回升，而不予补充维生素Ｂ＿２者的红细胞ＧＲ活性继续下降。光疗的时间越长，红细胞ＧＲ活性的下降越明显，补充维生素Ｂ＿２使红细胞ＧＲ活性回复到正常水平所需的时间也越长。短期光疗也可引起体内维生素Ｂ＿２的降解，导致红细胞ＧＲ活性的下降，为避免因红细胞ＧＲ活性下降引起的红细胞额外破坏，对接受光疗的黄疸新生儿常规补充维生素Ｂ＿２的是必要的。
The authors observed the activity of glutathione reductase (GR) in erythrocytes of jaundiced neonates before and after phototherapy with oral vitamin B_2 (43 cases) and without oral vitamin B_2 (17 cases) . The results showed that neonatal jaundice receiving short-term phototherapy of erythrocyte GR activity than before phototherapy GR activity decreased significantly after oral administration of vitamin B 2 can make the decline of erythrocyte GR activity was rebound, while those who did not receive vitamin B 2 erythrocyte GR activity Continue to decline. The longer the phototherapy, the more obvious decline of erythrocyte GR activity, vitamin B_2 to make the erythrocyte GR activity returned to the normal level of the longer time. Short-term phototherapy can also cause the degradation of vitamin B 2 in the body, which leads to the decrease of erythrocyte GR activity. To avoid additional destruction of erythrocytes caused by the decrease of erythrocyte GR activity, it is necessary to routinely supplement vitamin B 2 in neonates with jaundice receiving phototherapy.