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对421例采用醋酸甲孕酮150mg作为三个月注射一针避孕妇女的月经情况进行了分析。结果:随着用药时间增加闭经的比例越来越高,哺乳与非哺乳组闭经之间的差异越来越小;闭经者停用药物后月经逐渐恢复,末次注药后9个月内达到85.6％,21个月达到100％;用药时间的长短(1-6针)与闭经后月经恢复的时间长短无关;月经紊乱者恢复正常月经的时间(中位数)为7·8(2～22)月。结论:醋酸甲孕酮作为长效避孕针可引起月经的变化,随着用药时间增长闭经增多,但可逆,停药后可恢复。
Analysis of menstrual status of 421 women taking 150 mg of medroxyprogesterone acetate as contraception for three months. Results: As the proportion of amenorrhea increased with time, the difference between amenorrhea in nursing and non-breast-feeding groups became smaller and smaller. Menstruation gradually recovered after drug withdrawal in amenorrhea, and reached 85.6 within 9 months after the last injection %, 21 months to reach 100%; the duration of medication (1-6 stitches) has nothing to do with the duration of menstruation recovery after menopause; menstrual disorders were normal menstruation time (median) was 7.8 (2 ~ 22 )month. Conclusion: Medroxyprogesterone acetate as a long-acting contraceptive needle can cause changes in menstruation. With the increase of medication time, the amenorrhea increased, but reversible and recoverable after withdrawal.