老年性黄斑变性的发病机理尚未充分阐明,但从流行病学调查、临床及实验室研究中已知遗传、光损伤、营养缺乏、中毒、免疫异常、心血管及呼吸系统疾患以及原先存在的眼病都与之有关。这些因素可单独或协同地造成统称为老年性黄斑变性的临床异常。一、流行病学的研究流行病学调查是寻找危险致病因子的重要的第一步,最近美国、加拿大、英国等地的调查提 The pathogenesis of age-related macular degeneration has not been fully elucidated, but genetic, photodamage, immunodeficiency, immunodeficiency, cardiovascular and respiratory disorders and preexisting ophthalmopathy are known from epidemiological, clinical, and laboratory studies Related to it. These factors alone or in combination can cause clinical abnormalities collectively referred to as age-related macular degeneration. First, the epidemiological study Epidemiological investigation is to find a dangerous first step in the risk factors, the recent survey of the United States, Canada, Britain and other places to mention