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【目的】通过对18～24月龄婴幼儿进行早期孤独症谱系障碍(autism spectrum disorders,ASD)筛查并随访3年,了解深圳市ASD的患病率及早期诊断的可行性。【方法】用婴幼儿孤独症检测表(Checklist for autism intodalers,CHAT)量表对深圳市南山区、宝安区和龙岗区的3 624名婴幼儿进行筛查,对筛查阳性者进行转诊、电话访谈、诊断评估及3年随访。【结果】筛查阳性婴幼儿244人,总筛查阳性率为5.77%;共诊断ASD儿童10名,其中3例PDD-NOS,7例孤独症,总患病率为2.76‰,均为男性。第一次诊断评估为可疑ASD患儿在3年随访后仍旧符合ASD的诊断标准。【结论】深圳市ASD患病率低于国外报道结果,高于国内其他地区的报道。利用儿童保健系统进行孤独症的早期筛查具有可行性,有利于孤独症的早期诊断和早期干预。
【Objective】 To investigate the prevalence of ASD and the feasibility of early diagnosis of ASD in 18 ~ 24-month-old infants and young children by screening for autism spectrum disorders (ASD) and follow-up for 3 years. 【Methods】 A total of 3624 infants and young children in Nanshan District, Bao’an District and Longgang District of Shenzhen were screened by Checklist for Autism Intodators (CHAT) scale, and the screening positive persons were referred. Telephone interview, diagnostic evaluation and 3-year follow-up. 【Results】 A total of 244 positive infants were screened, the positive rate of screening was 5.77%. There were 10 ASD children diagnosed, including 3 PDD-NOS and 7 autism, the total prevalence was 2.76 ‰, . The first diagnostic assessment is that children with suspected ASD still meet the diagnostic criteria for ASD at 3 years of follow-up. 【Conclusion】 The prevalence of ASD in Shenzhen is lower than that reported abroad, higher than that reported in other regions of China. The early screening of autism using the child health system is feasible and facilitates the early diagnosis and early intervention of autism.