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目的:评价经皮球囊二尖瓣成形术(PBMV)的长期临床疗效。方法:采用改良In-oue方法对143例风湿性二尖瓣狭窄患者行PBMV治疗,并对其中140例患者进行了术后长期随访。结果:与术前相比,术后二尖瓣口面积(MVA)增大[(1.03±0.55)cm~2对(2.03±0.37)cm~2],二尖瓣跨瓣压差(MVG)降低[(18.1±4.8)mmHg对(4.1±2.3)mmHg],左心房内径(LAD)减小[(4.67±1.10)cm对(4.13±0.59)cm],P<0.001。平均随访(90±24)个月时MVA(1.73±0.48)cm~2,MVG(6.5±3.4)mmHg,LAD(4.21±0.82)cm。29例患者发生了再狭窄,再狭窄率为20.7％。结论:PBMV术后长期临床疗效良好。
Objective: To evaluate the long-term clinical efficacy of percutaneous balloon mitral valvuloplasty (PBMV). Methods: 143 patients with rheumatic mitral stenosis were treated with PBMV by modified In-oue method and 140 patients were followed up for a long period. Results: Compared with the preoperation, MVA increased ([(1.03 ± 0.55) cm ~ 2 vs (2.03 ± 0.37) cm ~ 2], mitral valve pressure difference (4.17 ± 1.10) cm vs (4.13 ± 0.59) cm], P <0.001. There was no significant difference between the two groups (P> 0.05). MVA (1.73 ± 0.48) cm ~ 2, MVG (6.5 ± 3.4) mmHg and LAD (4.21 ± 0.82) cm were observed on the average follow-up of 90 ± 24 months. Restenosis occurred in 29 patients and the rate of restenosis was 20.7%. Conclusion: Long-term clinical efficacy of PBMV after surgery is good.