国外多采用前列腺素抗早孕,但价格昂贵,不易推广使用。国内也尚无一个较满意的抗早孕药物。重庆市第四人民医院妇产科等,采用新洁尔灭宫腔给药,试用于356例早期流产,得到满意效果,有效率80%左右,对35天左右孕龄尤为有效,成功率达95.6%,相当于前列腺素的抗早孕效果。为此,我们进行了新洁尔灭的动物试验和毒性研究,简报如下。 Foreign use of prostaglandin anti-early pregnancy, but expensive, not easy to promote use. There is no more satisfactory anti-pregnancy drug in China. Chongqing Fourth People’s Hospital Obstetrics and Gynecology, the use of benzalkonium treatment of intrauterine administration, trial of 356 cases of early abortion, with satisfactory results, the effective rate of about 80%, about 35 days gestational age is particularly effective, the success rate of 95.6% Equivalent to the prostaglandin anti-pregnancy effect. To this end, we conducted a pilot study on the toxicity and toxicity of benzalkonium bromide, briefly presented below.