论文部分内容阅读
采用流式细胞术(FCM)对41例子宫内膜癌病例及8例正常于宫内膜病例的石蜡包埋标本进行回顾性分析。结果表明:①8例正常子宫内膜均为二倍体,而41例子宫内膜癌其异倍体率高达75.6%,(31/41例)。DI、PI及SPF值明显高于对照组(P<0.05)。②异倍体分布与病理分级具有相关性。且异倍体瘤死亡率明显增高(P<0.05)。③DNA含量、肿瘤倍体可作为子宫内膜癌早期诊断、区分良恶程度、判断预后的重要指标。
Forty-one cases of endometrial cancer and eight cases of paraffin-embedded specimens normal to endometrium were retrospectively analyzed by flow cytometry (FCM). The results showed that: ①8 cases of normal endometrium were diploid, and 41 cases of endometrial cancer aneuploidy rate as high as 75.6%, (31/41 cases). DI, PI and SPF were significantly higher than the control group (P <0.05). ② aneuploidy and pathological grade has a correlation. And aneuploid tumor mortality was significantly higher (P <0.05). ③ DNA content, tumor ploidy can be used as early diagnosis of endometrial cancer, the distinction between benign and malignant, an important indicator of prognosis.