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目的探讨生长抑素8肽(善宁)治疗溃疡性上消化道出血的疗效。方法选择58例急性溃疡性上消化道中、大量出血患者,随机分成二组。对照组31例用西咪替丁治疗,观察组27例用善宁治疗,观察用药后24、48h止血情况。结果对照组止血有效率为67.74%,观察组止血率为92.59%,二组比较差异有统计学意义(P<0.05),治疗过程未见不良反应。结论善宁治疗溃疡性上消化道出血的疗效显著,安全可靠,值得推广应用。
Objective To investigate the efficacy of somatostatin 8 peptide (Shanning) in the treatment of ulcer upper gastrointestinal bleeding. Methods A total of 58 cases of acute ulcer in the upper digestive tract, a large number of bleeding patients were randomly divided into two groups. In the control group, 31 cases were treated with cimetidine. In the observation group, 27 cases were treated with Shanning, and the hemostasis was observed 24 and 48 hours after treatment. Results The effective rate of hemostasis in control group was 67.74%, and the rate of hemostasis in observation group was 92.59%. There was significant difference between the two groups (P <0.05). No adverse reaction was observed during the treatment. Conclusion Shannon treatment of ulcerative upper gastrointestinal bleeding significant effect, safe and reliable, it is worth promoting the application.