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分析测定16例糖尿病、11例脑梗塞、45例高血压、26例冠心病、27例肝硬化、17例其他疾病(胃炎、慢支等)及63例正常人的血清高密度脂蛋白胆固醇(HDL-Ch)及其亚组分胆固醇(HDL_2-Ch,HDL_2-Ch)。结果:前五种疾病的 HDL-Ch 均显著降低(P<0.01),其亚组分除糖尿病和高血压病的 HDL_3-Ch 及肝硬化的 HDL_2-Ch 无明显降低(P>0.05)外,余项均显著降低(P<0.01)。17例其他疾病的以上三项均值则无明显降低(P>0.05)。提示:HDL-Ch 及其亚组分的测定对动脉粥样硬化病变及肝脏病变的诊断具有重要的辅助意义。
Analysis and determination of 16 cases of diabetes, 11 cases of cerebral infarction, 45 cases of hypertension, 26 cases of coronary heart disease, 27 cases of liver cirrhosis, 17 cases of other diseases (gastritis, chronic bronchitis, etc.) and 63 normal people serum high density lipoprotein cholesterol HDL-Ch) and its sub-component cholesterol (HDL_2-Ch, HDL_2-Ch). Results: HDL-Ch in the first five diseases was significantly decreased (P <0.01). The HDL-3-Ch in sub-components of diabetes and hypertension and HDL-2-Ch in cirrhosis were not significantly decreased (P> 0.05) The remaining items were significantly lower (P <0.01). 17 cases of other diseases, the above three mean no significant reduction (P> 0.05). Hint: The determination of HDL-Ch and its sub-components has important adjuvant significance in the diagnosis of atherosclerotic lesions and liver lesions.