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在英明领袖华主席抓纲治国战略决策指引下,最近我厂试验从奋乃静生产下脚羟哌高沸物制取1,4-双羟乙基哌嗪(结构式为HOCH_2CH_2--CH_2CH_2OH)取得了成功。产品质量符合文献标准,熔点为134～138℃双羟乙基哌嗪的回收,不但减少了浪费,主要的是它可以作为合成新药三哌喹的主要原料,也是三甲氧基苯酰嗪的主要中间体。三哌喹是长效低毒的抗疟新药,其化学名称:1,4-双[1-(7-氯-4-喹啉)-4-乙基哌嗪基]哌嗪。
In the guidance of wise leader Chairman Hua Gangguo strategic decision, under the guidance of my factory recently test perphenazine from the production of high-hydroxyl-piperazine Preparation of 1,4 - bishydroxyethylpiperazine (structural formula HOCH_2CH_2 - CH_2CH_2OH) made success. Product quality in line with the literature standards, the melting point of 134 ~ 138 ℃ bishydroxyethylpiperazine recovery, not only reduces the waste, the main is that it can be used as the main raw material for the synthesis of new drug tripezil, but also the main trimethoxybenzoyl Intermediate. Tripipequine is a long-acting, low-toxicity anti-malarial drug whose chemical name is 1,4-bis [1- (7-chloro-4-quinoline) -4-ethylpiperazinyl] piperazine.