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目的探讨血栓弹力图(TEG)在脑部肿瘤术后凝血功能异常患者临床输血中的应用效果。方法将38名脑部肿瘤术后凝血功能异常患者随机分为2组:常规检测输血组(对照组)和TEG检测输血组(实验组),每组各19名。对照组依据凝血4项检测结果,实验组依据TEG的实验数据指导临床输血。对照组血液输注前及输注后24h检测凝血4项,实验组在对照组检测基础上增加TEG检测,观察患者的凝血状况和血液的使用情况。结果临床输血治疗后2组患者的PT、APTT和TT均有显著缩短(P<0.01),FIB显著增加(P<0.01)。其中,实验组患者的凝血功能异常改善好于常规组(P<0.05),实验组患者输注血液前、后TEG检验指标显著改善,差异有统计学意义(P<0.01);实验组的CRC和FFP使用量低于常规组(P<0.05)。结论 TEG和常规检测相比,能更好地指导脑部肿瘤术后凝血功能异常患者的血小板等血液成分的输注。
Objective To investigate the clinical application of thrombus elastography (TEG) in the clinical blood transfusion of patients with coagulation dysfunction after brain tumor surgery. Methods Thirty-eight patients with postoperative coagulation dysfunction of brain tumor were randomly divided into two groups: conventional blood transfusion group (control group) and TEG transfusion group (experimental group), 19 in each group. The control group was based on the four blood coagulation test results, the experimental group based on TEG experimental data to guide clinical blood transfusion. Control group before blood transfusion and 24h after infusion of coagulation test 4, the experimental group in the control group based on the detection of increased TEG to observe the patient’s coagulation status and blood usage. Results The PT, APTT and TT were significantly shortened (P <0.01) and FIB increased significantly (P <0.01). Among them, the improvement of coagulation dysfunction in the experimental group was better than that in the conventional group (P <0.05). The TEG test index was significantly improved in the experimental group before and after the infusion of blood (P <0.01) And FFP were lower than the conventional group (P <0.05). Conclusion Compared with routine testing, TEG can better guide the transfusion of blood components such as platelets in patients with coagulation dysfunction after brain tumor surgery.