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鼠实验研究业已证明锌缺乏导致纤维组织形成期皮肤切口的抗裂强度降低。本文旨在观察锌缺乏对疤痕再塑期一期缝合皮肤切口的抗裂强度和胶原成分的影响。共进行两项实验:(1)取鼠20只,不手术,喂饲特殊饲料,14天后测血清、皮肤和肝内锌浓度。(2)取鼠18只,喂饲特殊饲料14天后在乙醚等麻醉下作一4cm长腹部正中切口,直至腹膜,然后分层缝合腹膜和白线以及皮肤。术后21天杀死动物,取下伤口皮肤,分别测抗裂强度、羟脯氨酸含量以及皮
Experimental studies in rats have demonstrated that zinc deficiency leads to a decrease in the rupture strength of skin incisions during fibrogenesis. This article aims to observe the effect of zinc deficiency on the rupture strength and collagen composition of primary incision skin incision in scar remodeling. A total of two experiments: (1) take 20 rats, no surgery, feeding special feed, 14 days after the test serum, skin and liver zinc concentration. (2) Take 18 rats, feed 14 days after special feed and make a 4cm incision in the middle of the abdomen under anesthesia such as ether until the peritoneum, and then stratify the peritoneum, white line and skin. The animals were sacrificed 21 days after the operation and the skin of the wounds was removed and the rupture strength, hydroxyproline content, and skin