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目的探讨甲亢有效的治疗方法,提高患者的生活质量。方法100例符合条件的患者随机分为观察组和对照组各50例,观察组采用131Ⅰ治疗,对照组采用他巴唑治疗,比较两组患者的临床疗效、甲状腺功能低下(甲低)发生率及复发率和突眼发生率。结果观察组治愈36例(72.00%),好转11例(22.00%),无效3例(6.00%);对照组治愈15例(30.00%),好转26例(52.00%),无效9例(18.00%),两组疗效比较,观察组明显高于对照组(P<0.01)。甲低发生率和治愈后甲亢复发率存在差异(P<0.01)。结论131Ⅰ治疗甲亢效果优于他巴唑,疗效肯定、安全,具有一定的临床价值,值得临床应用推广。
Objective To investigate the effective treatment of hyperthyroidism and improve the quality of life of patients. Methods 100 cases of eligible patients were randomly divided into observation group and control group of 50 patients, the observation group with 131 Ⅰ treatment, the control group with methimazole treatment, the two groups of patients with clinical efficacy, hypothyroidism (hypothyroidism) incidence And recurrence rate and exophthalmos incidence. Results The observation group was cured in 36 cases (72.00%), improved in 11 cases (22.00%), ineffective in 3 cases (6.00%), control group cured in 15 cases (30.00%), improved in 26 cases (52.00% %). The curative effect of the two groups was significantly higher than that of the control group (P <0.01). The prevalence of hypothyroidism and the recurrence rate of hyperthyroidism after treatment were different (P <0.01). Conclusion 131 Ⅰ is superior to methimazole in the treatment of hyperthyroidism. The curative effect is definite and safe, and it has certain clinical value. It is worth to be popularized clinically.