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目的:分析支气管哮喘急性发作期的特点,探讨采用小青龙汤加减联合布地奈德治疗支气管哮喘急性发作期的效果,为临床提供经验。方法:选取112例诊断为支气管哮喘急性发作的患者,随机分为对照组和治疗组,两组均采用常规的方法进行治疗(均使用布地奈德气雾剂),治疗组在对照组的基础上根据患者的实际情况辨证使用小青龙汤,两组均连续治疗2周,考察两组的临床治疗效果,症状、体征评分及主要生理指标复常时间等。结果:经治疗后,对照组总有效率为82.1%,治疗组为98.2%,治疗组总有效率较对照组有显著性差异(χ2=4.181,P<0.05);治疗组症状、体征改善程度较对照组有显著性差异(t=7.274,P<0.05);治疗组咳嗽、气喘、湿罗音及哮鸣音的复常时间较对照组明显缩短,具有显著性差异(P<0.05)。结论:在常规治疗的基础上,辨证使用小青龙汤及布地奈德用于治疗支气管哮喘急性发作期,可使主要生理指标迅速恢复正常,改善患者的临床状况,提高临床治疗效果,具有一定的临床借鉴意义。
OBJECTIVE: To analyze the characteristics of acute exacerbation of bronchial asthma and explore the effect of Xiao Qing Long Decoction combined with budesonide in the treatment of acute exacerbation of bronchial asthma, so as to provide clinical experience. Methods: One hundred and twelve patients diagnosed as acute exacerbation of bronchial asthma were randomly divided into control group and treatment group. Both groups were treated by conventional method (using budesonide aerosol). The treatment group was basal in control group On the basis of the actual situation of patients using Xiaoqinglong Decoction, two groups were treated for 2 weeks, to examine the clinical efficacy of the two groups, symptoms, signs and major physiological indicators of normal time and so on. Results: After treatment, the total effective rate was 82.1% in the control group and 98.2% in the treatment group. The total effective rate in the treatment group was significantly different from that in the control group (χ2 = 4.181, P <0.05). The improvement of symptoms and signs in the treatment group (T = 7.274, P <0.05). The recovery time of cough, asthma, rales and wheeze in treatment group were significantly shorter than those in control group (P <0.05). Conclusion: On the basis of routine treatment, Xiao Qing Long Decoction and budesonide can be used to treat the acute exacerbation of bronchial asthma, which can quickly return the main physiological indicators to normal, improve the clinical status of patients and improve the clinical curative effect, with certain Clinical reference significance.