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1987～1996年对22个省（市、区）的60个县、区进行了莱姆病的调查研究。血清流行病学证实22个省（市、区）林区人群均存在莱姆病感染，感染率平均为5．06％（1724／34104）。病原学证实17个省（市＼区）存在莱姆病自然疫源地。11个省（市、区）有典型病例存在。东北林区患病率为1％～4％。全沟硬蜱是我国北方林区莱姆病螺旋体的主要生物媒介，南方的粒形硬蜱和二棘血蜱在传播中可能起重要作用。姬鼠属可能是莱姆病螺旋体的主要贮存宿主。从病人、蜱或动物中分离出130株莱姆病螺旋体，中国菌株SDS－PAGE蛋白图形、质粒谱和DNA限制性内切酶谱与北美菌株显著不同。rRNA基因多态性分析，中国菌株可被分为三个基因种，其中第一基因种（B．burgdorferisensustricto）在亚洲是首次发现.
From 1987 to 1996, Lyme disease was investigated in 60 counties and districts in 22 provinces (cities and districts). Serological epidemiology confirmed that all the 22 provinces (municipalities and districts) had Lyme disease infection, with an average infection rate of 5.06% (1724/34104). Etiology confirmed 17 provinces (cities districts) Lyme disease natural foci. 11 provinces (cities, districts) there are typical cases exist. The prevalence of forest in Northeast China is 1% ~ 4%. Ixodes Ixodes is the major biological vector of Borrelia burgdorferi in the northern forestlands of our country. It may play an important role in spreading. Apodemus may be the main storage host for Lyme disease. Of the 130 Lyme disease spirochetes isolated from patients, ticks or animals, the SDS-PAGE protein patterns, plasmid profiles and DNA restriction endonuclease patterns of Chinese strains were significantly different from those of North American strains. rRNA gene polymorphism analysis, Chinese strains can be divided into three genotypes, of which the first genus (B. burgdorferisensustricto) was first found in Asia.