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以柯萨奇Ｂ组病毒（ＣＶＢ）感染的组织细胞为抗原，用间接免疫酶标法测定１０５例病毒性心肌炎（ＶＭＣ）患儿血清ＣＶＢ的ＩｇＭ抗体，与５９例其他病患儿（ＣＯＤ）和６７名健康儿童（ＨＣ）的结果比较，发现：ＶＭＣ组ＩｇＭ的几何平均滴度（ＧＭＴ），女性高于男性，（Ｐ＜０．０５）；且男女都高于ＨＣ组（Ｐ＜０．０１）。与ＣＯＤ相比，女性高于ＣＯＤ组，而男性无统计学意义。男女合并，如以滴度１１０作为ＩｇＭ诊断儿童ＶＭＣ的阳性标准，鉴别ＶＭＣ与ＣＯＤ和ＨＣ的符合率分别为６５．８５％和８３．７２％。表明ＣＶＢ－ＩｇＭ抗体用于儿童ＣＶＢ心肌炎的诊断有一定的参考价值。
IgM antibodies against CVB in 105 patients with viral myocarditis (VMC) were detected by indirect immunoenzymatic assay with CVB-infected tissue cells, and 59 patients with other disease (COD) (HCT) in 67 healthy children (HC). The results showed that the geometric mean titer (GMT) of IgM in VMC group was higher than that of male (P <0.05) .01). Compared with COD, women were higher than COD group, while men had no statistical significance. If the titer of 110 was used as the positive standard for diagnosis of VMC in children, the coincidence rates of VMC and COD and HC were 65.85% and 83.72% respectively. That CVB-IgM antibodies for the diagnosis of CVB myocarditis in children with a certain reference value.