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目的:比较早期乳腺癌保乳手术与改良根治手术的临床效果,探讨治疗早期乳腺癌的最佳手术方案。方法:选择早期乳腺癌患者138例,根据自愿的原则,分为保乳组(BCS)和根治组(MRS),保乳组采取保乳手术方案,根治组采用改良根治手术方案,比较两组患者手术时间、术中出血量、切口长度、住院时间、术后并发症、美容效果满意率及患者预后情况。结果:两组患者手术时间、术中出血量、切口长度、住院时间、术后并发症、美容效果满意率比较,差异具有(高度)统计学意义(P<0.01,P<0.05);术后12个月、18个月和24个月复发或死亡例数比较,差异无统计学意义(P>0.05)。结论:早期乳腺癌患者外科手术治疗时,应首选保乳手术方式治疗。
Objective: To compare the clinical effects of conservative breast-conserving surgery and modified radical mastectomy to explore the best surgical treatment for early-stage breast cancer. Methods: 138 patients with early breast cancer were selected. According to the principle of voluntariness, BCS and MRS were divided into two groups: breast-conserving surgery group and breast-conserving group with modified radical mastectomy. Patient operation time, intraoperative blood loss, incision length, hospitalization time, postoperative complications, cosmetic satisfaction rate and prognosis of patients. Results: There was significant difference between the two groups in the operation time, blood loss, incision length, hospitalization time, postoperative complications and satisfaction rate of cosmetic effect (P <0.01, P <0.05) There were no significant differences in the number of recurrent or death cases at 12 months, 18 months and 24 months (P> 0.05). Conclusion: Breast-conserving surgery should be the first choice for surgical treatment of patients with early-stage breast cancer.