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对68例PCOS的临床表现进行了研究。对其中62例随机选用①单纯中药,②单纯卵巢楔切术,③楔切+克罗米芬,④克罗米芬不同用量及方法,以BBT为中心,进行疗效研究。结果显示:本症多发于25～29岁(76.47％)。多毛占64.67％;肥胖占45.58％;不妊占100％;月经障碍以Ⅰ度闭经为主,占48.52％;BBT单相占97.06％;卵巢增大占94.12％;子宫内膜活检19/22例(86.37％),有不同程度增生;阴道涂片65/66例(98.98％),有一定雌激素影响;17—OHCS、17—KS多在正常范围。总排卵率80.64％,排卵周期率65.22％,妊娠率46.77％,流产率25％。比较各组排卵率及排卵周期率,均以楔切+克罗米芬为最佳(P<0.001),但妊娠率各组间无大差异(P>0.05)。对克罗米芬不同用量及用法的疗效,也进行了比较,并对PCOS的诊断与治疗,提出我们的看法。
68 cases of PCOS clinical manifestations were studied. 62 cases were randomly selected ① pure Chinese medicine, ② simple ovarian wedge resection, ③ Wedge cut + clomiphene citrate ④ different dosage and methods, with BBT as the center for efficacy study. The results showed that: The disease occurs in 25 to 29 years old (76.47%). Hirsutism accounted for 64.67%; obesity accounted for 45.58%; not pregnant accounted for 100%; menstrual disorders with a degree of amenorrhea mainly accounted for 48.52%; BBT single phase accounted for 97.06%; ovarian enlargement accounted for 94.12%; endometrial biopsy 19/22 cases (86.37%), with varying degrees of proliferation; vaginal smear 65/66 cases (98.98%), a certain estrogen effect; 17-OHCS, 17-KS and more in the normal range. The total ovulation rate was 80.64%, ovulation cycle rate was 65.22%, pregnancy rate was 46.77% and abortion rate was 25%. Ovulation rate and ovulation cycle rate of each group were compared, the best wedge cutting + clomiphene citrate (P <0.001), but the pregnancy rate was no significant difference between the groups (P> 0.05). The effect of different dosage and usage of clomiphene has also been compared, and we put forward our opinion on the diagnosis and treatment of PCOS.