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目的了解2010—2014年深圳市龙岗区平湖街道疑似预防接种异常反应(adverse event following immunization,AEFI)发生特征,以评价国家免疫规划疫苗的安全性和预防接种服务质量。方法采用描述流行病学方法对2010—2014年报告的AEFI监测结果进行分析。结果 2010—2014年共报告AEFI病例271例,社区覆盖率为100.00%。以一般反应为主,占报告总数的71.22%,异常反应占28.78%。AEFI平均发生率为5.08/10万针次,以无细胞性百白破疫苗发生率最高(1.07/10万针次)。全年均有病例报告,3—10月报告病例数较多;0~2岁年龄组报告数最多,占报告病例数的75.64%。结论深圳市龙岗区平湖街道疑似AEFI发生率较低,无疫苗质量事故及接种事故的报告,疫苗安全性和预防接种服务质量良好。
Objective To understand the occurrence of suspected AEFI in Pinghu Street, Longgang District, Shenzhen from 2010 to 2014 so as to evaluate the safety of vaccines and vaccination services. Methods Descriptive epidemiological methods were used to analyze the AEFI monitoring results reported in 2010-2014. Results A total of 271 AEFI cases were reported in 2010-2014, with a community coverage rate of 100.00%. The general reaction, accounting for 71.22% of the total number of reports, anomalous reactions accounted for 28.78%. The average incidence of AEFI was 5.08 / 100,000 needle-times, with the highest incidence of acellular diphtheriae vaccine (1.07 / 100,000 needles). There were case reports throughout the year, with a larger number of cases reported in March-October; the highest number reported in the 0-2 age group, accounting for 75.64% of the reported cases. Conclusions The incidence of suspected AEFI in Pinghu Street, Longgang District, Shenzhen is relatively low. There is no report of vaccine accident and vaccination accident. The vaccine safety and vaccination service are of good quality.