病历摘要李××,女,27岁,已婚,住院号84,071,因不规则皮肤色素沉着1年半,心悸、气促半年,指趾刺痛发紫4个月入院。患者于1年半前无明确诱因发现面部有褐色色素斑,波及额、颧、额及耳廓,无痛痒,随后四肢、腹部相继出现,颜色日深,同时毛发、眉毛、阴毛脱落,面有紧张感。半年前始活动时出现心悸、气促,无咳嗽、咯痰,无夜间端坐呼吸。症状日渐加剧,间有下肢水肿。4个月前在接触冷水时手足发麻、刺痛,指趾先苍白后发紫,取暖后转红、麻木消失。反复发作,日渐频数、延续、渐感手 Medical records Li × ×, female, 27 years old, married, hospital number 84,071, due to irregular skin pigmentation for 1 year and a half, heart palpitations, shortness of breath for six months, finger toe sting purple 4 months admission. Patients with a clear cause of brown spots on the face a year and a half ago, affecting the amount, zygomatic, frontal and auricle, itching, followed by limbs, abdomen have appeared, the color of the dark, while the hair, eyebrows, pubic hair off, face Tension. Half a year ago when the event of palpitations, shortness of breath, no cough, expectoration, no night-time sitting breathing. Increasing symptoms, between the lower extremity edema. 4 months ago in contact with cold water when numb hands and feet, stinging, toe first purple pale after heating turn red, numbness disappeared. Repeated attacks, increasing frequency, continuation, gradually senses