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自从Warren和Mashall于1983年首次从胃粘膜中分离出幽门螺杆菌(HP)以来,关于HP及其相关疾病的研究一直方兴未艾.近年来越来越多的研究表明HP与胃癌的发生间存在着密切的关系,本文就这方面的研究进展作一简要综述.1 HP与胃癌的流行病学大量流行病学研究表明HP流行与胃癌的流行有很多相似之处.HP感染者发生胃癌的危险性较非感染者高6倍.就世界范围看,某些发展中国家如秘鲁、哥伦比亚及中国HP感染率较高,其胃癌
Since Warren and Mashall first isolated H. pylori (HP) from the gastric mucosa in 1983, research on HP and its related diseases has been on the rise. In recent years, more and more studies have shown that there is a relationship between HP and gastric cancer. Closely related, this article provides a brief review of the research progress in this area. 1 Epidemiology of HP and Gastric Epidemiology A large number of epidemiological studies have shown that the HP epidemic has many similarities with the epidemic of gastric cancer. The risk of gastric cancer in HP infected individuals 6 times higher than non-infected persons. On a global scale, HP infection rate is high in some developing countries such as Peru, Colombia, and China.