回顾近15年有关中西医结合治疗胰腺癌的病因病机、临床研究及实验研究。脾胃受损,湿热毒邪外侵是其总的病因病机。然对该病的中医辨证分型尚无统一标准,大致可分为热毒蕴结型、肝胆湿热、脾虚湿阻型、肝阴亏虚型。治疗上以中西医结合为主,中药的运用可显著减轻西医疗法的不良反应,提高疗效,然仍存在一定的问题,如缺乏大样本的临床研究等。但中医药联合西医在未来胰腺癌的综合治疗中发挥的协同作用,尤其是中药多靶点调节机体免疫从而发挥抗癌作用值得关注和研究。 Review of nearly 15 years on the etiology and pathogenesis, clinical research and experimental research of integrated traditional Chinese and Western medicine in the treatment of pancreatic cancer. Spleen and stomach damage, damp heat poisoning is the total etiology and pathogenesis. However, the TCM syndrome differentiation of the disease there is no uniform standard, can be divided into heat toxic accumulation type, liver and gallbladder dampness, spleen dampness type, liver yin deficiency type. The combination of Chinese and Western medicine treatment based on the use of traditional Chinese medicine can significantly reduce the adverse reactions of Western medicine to improve the curative effect, but there are still some problems, such as the lack of a large sample of clinical research. However, traditional Chinese medicine combined with Western medicine in the future comprehensive treatment of pancreatic cancer play a synergistic effect, in particular, multiple targets of traditional Chinese medicine to regulate immunity and thus play an anti-cancer role worthy of attention and research.