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根据Manning等的研究,四氯乙烯对姜片虫感染的疗效胜过已雷琐辛。但在服用时四氯乙烯药丸不可咬破,对儿童给药造成困难。再则此药毒性虽然较小而副反应较多。氯硝柳胺对多种绦虫及肠道异形吸虫感染均有效且无毒,其作用为抑制绦虫线粒体的氧化磷酸化过程,虫体接触该药后死亡,并从大便排出。药片可以咬碎,方便儿童服用,对肝、肾、造血系统等均无害。作者在曼谷对40例姜片虫感染的儿童和青年进行上述两种药的疗效比较,其中13例用四氯乙烯标准疗法,27例用氯硝柳胺治疗。治前每例进行
According to Manning et al., The efficacy of tetrachlorethylene in the infection of zooxanthellae is better than that of lexosin. But when taking PCE pills can not be broken, causing difficulties for children’s medication. And then the drug toxicity though smaller and more side effects. Niclosamide is effective and nontoxic to many kinds of tapeworms and intestinal microflora, and its role is to inhibit the oxidative phosphorylation of tapeworm. The insects die after contacting with the drug and excreting it from the stool. Pills can be crushed, easy to take for children, the liver, kidney, hematopoietic system, etc. are harmless. The authors compared the efficacy of the two drugs in 40 children and young adults infected with Ginger’s worm in Bangkok, of which 13 were treated with tetrachlorethylene standard and 27 were treated with niclosamide. Each case before the treatment