More and more out of core problems that involve solving large amounts of data are researched by scientists. The computational grid provides a wide and scalable environment for those large scale computations. A new method supporting out of core computations on grids is presented in this paper. The framework and the data storage strategy are described, based on which an easy and efficient out of core programming interface is provided for the programmers. More and more out of core problems that,772,734,727,727,772,750,750,750,750,782,782,782,782,782,745,745,745,760,745,760,545,545,545,545,545,545,545,545,545,545,545,545,760 and the cost of large quantities of data are raised by scientists. The computational grid provides a wide and scalable environment for those large scale computations. The framework and the data storage strategy are described, based on which an easy and efficient out of core programming interface is provided for the programmers.