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目的:探讨基于时机理论的动机性访谈对婴儿痉挛症患儿父母自我效能、负性情绪及应对方式的干预效果。方法:采用整群抽样法选取2019年1—10月在湖南省儿童医院神经内科住院的82例婴儿痉挛症患儿父母为研究对象，按随机数字表法分为对照组和观察组各41例。对照组实施以家庭为中心的护理及健康教育，观察组在对照组基础上实施5次基于时机理论的动机性访谈干预。于干预前、出院当天、出院后3个月采用一般自我效能感量表（GSES）、医院焦虑抑郁量表（HADS）、中文版父母用应对方式量表（CHIP）评价干预效果。结果:干预前，2组患儿父母GSES、HADS-A、HADS-D及CHIP各分量表得分比较差异无统计学意义（n P>0.05）。干预后观察组在出院当天、出院后3个月的GSES得分分别为（19.63 ± 0.87）、（22.58 ± 1.28）分，明显高于对照组的（18.92 ± 0.74）、（19.46 ± 1.25）分，差异有统计学意义（n t值为-3.865、-10.926，n P<0.01）；干预后观察组在出院当天、出院后3个月的HADS-A/HADS-D得分分别为（12.50 ± 0.82）、（10.50 ± 0.87）分和（9.78 ± 0.80）、（8.63 ± 0.87）分，低于对照组的（12.92 ± 0.74）、（11.72 ± 0.99）分和（10.23 ± 0.78）、（9.38 ± 1.04）分，差异有统计学意义（n t值为2.412~5.764，n P<0.05或0.01）；干预后观察组在出院当天、出院后3个月的CHIP各分量表得分均高于对照组，差异有统计学意义（n t值为-7.934~-2.490，n P0.05). After intervention, The GSES scores of the observation group on the day of discharge and 3 months after discharge were (19.63±0.87) and (22.58±1.28) points, which were significantly higher than (18.92±0.74) and (19.46±1.25) points of the control group. The difference between both groups was statistically significant (n t values were -3.865, -10.926, n P<0.01). HADS-A/HADS-D scores of the observation group on the day of discharge and 3 months after discharge were (12.50±0.82), (10.50±0.87) and (9.78±0.80), (8.63±0.87) points, respectively. The HADS-A/HADS-D scores of the control group on the day of discharge and 3 months after discharge were (12.92±0.74), (11.72±0.99) and (10.23±0.78), (9.38±1.04) points, respectively. The difference was statistically significant (n t values were 2.412-5.764, n P<0.05 or 0.01). The observation group scores on CHIP subscales on the day of discharge and 3 months after discharge are higher than the control group, the difference was statistically significant (t values were -7.93--2.490,n P<0.05 or 0.01).n Conclusions:Motivational interviews based on timing theory can enhance parents’ self-efficacy, improve their negative emotions and family coping styles, and thereby promote the recovery of children.