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在人体内溴的分布广泛,其确切生化作用尚未阐明。正常人血清溴含量为100～750μg/100ml,仅小部分与蛋白质或其它有机物质直接结合。血清溴含量过高即出现溴中毒。早年在 Johns Hopkins 医院住院的精神病病人,约有10%的血清溴含量过高,并伴有明显溴中毒症状。以后改用含溴少的药物,溴中毒发生率才降低。外科病人常用含溴量高的药物,如麻醉药氟烷(三氟溴氯乙烷)含溴百分率就高。使用这类药物后,血溴必然相应上升。氟烷在人体的分布及其确切机理
The distribution of bromine in the human body is widespread, and its exact biochemical effects have not yet been elucidated. Normal human serum bromine content of 100 ~ 750μg / 100ml, only a small part of the protein or other organic substances directly. Serum bromine content is too high that bromine poisoning. About 10% of patients with psychiatric illness who were hospitalized at Johns Hopkins Hospital in the early years had high levels of serum bromine accompanied by symptoms of bromine poisoning. After switching to less bromine-containing drugs, bromine poisoning was reduced. Surgical patients commonly used drugs containing high levels of bromine, such as narcotics, halothane (Trifluorobromoethane) containing high percentage of bromine. After using these drugs, blood bromine is bound to rise accordingly. HFA distribution in human body and its exact mechanism