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食管癌放疗后手术切除,国内外报道较多,但从病理角度分析者少。本文着意于分析放疗后病理改变与近、远期疗效的关系。1 材料和方法1979年1月至1981年12月病理活检为食管中段鳞癌后,治疗随机分组,见表1。~(60)钴术前放疗量3000～4500cGy。沿瘤体或瘤床纵行切取中心及两侧缘组织块。常规石蜡切片,H、E染色。2结果放疗的病理改变,主要为癌液化性和凝固性坏死。液化性坏死附加炎细胞及纤维母细胞反应性增生常较凝固性者为重,而形成结核样结节。其在各例
The surgical resection of esophageal cancer after radiotherapy has been reported at home and abroad, but there are few analysts from the pathological point of view. This article aims to analyze the relationship between pathological changes after radiotherapy and near and long-term efficacy. 1 Materials and Methods Randomization of treatment was performed after pathological biopsy from January 1979 to December 1981 as squamous cell carcinoma of the middle esophagus. ~ (60) Cobalt preoperative radiotherapy 3000 ~ 4500cGy. Along the tumor or the tumor bed, the center and both sides of the tissue block were cut longitudinally. Conventional paraffin sections, H, E staining. 2 Results Pathological changes in radiotherapy, mainly cancer liquefaction and coagulation necrosis. The liquefaction necrosis associated with inflammatory cells and fibroblasts is often more severe than coagulation, and tuberculous nodules are formed. In each case