Causality Diagram (CD) is a new graphical knowledge representation based on probability theory. The application of this methodology in the safety analysis of the gas explosion in collieries was discussed in this paper, and the Minimal Cut Set, the Minimal Path Set and the Importance were introduced to develop the methodology. These concepts are employed to analyze the influence each event has on the top event ( the gas explosion, so as to find out about the defects of the system and accordingly help to work out the emphasis of the precautionary work and some preventive measures as well. The results of the safety analysis are in accordance with the practical requirements; therefore the preventive measures are certain to work effectively. In brief, according to the research CD is so effective in the safety analysis and the safety assessment that it can be a qualitative and quantitative method to predict the accident as well as offer some effective measures for the investigation, the prevention and the control of the accident.