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我院肾脏科1980～1990年共收治溶血尿毒综合征(简称HUS)20例.死亡4例,其中2例经病理证实.本文将资料完整的14例报告如下.1 临床资料HUS特征是:突然出现的溶血性贫血及迅速进行的肾功能衰竭.可伴有中枢神经系统损害、胃肠道出血及血液学异常,包括红细胞破碎、血小板减少及微血管内凝血.本组14例均符合此特征.根据Kaplan的分型,本组重型8例,轻型6例.1.1 一般资料 男8例,女6例.男女之比为1.3:1;年龄1～3岁2例,1～7岁9例.8～14岁3例,平均年龄5.7岁 本组以学龄前儿童为主占61.3%,发病季节7～10月者共10例.1.2 症状与体征 有前驱症状12例,其中呼吸道感染5例,消化道感染7例.1.2.1 一般症状 颜面苍白13例,乏力14例,发热9例,黄染6例,消化道出血7例,皮肤粘膜出血6例.1.2.2 泌尿系统症状 11例有血尿,其中7例有肉眼血尿.全组均有蛋白尿,11倒尿蛋白达(卌).高血压5
Nephrology, our hospital from 1980 to 1990, a total of 20 cases of hemolysis-uremic syndrome (HUS), 4 patients died, of which 2 cases were confirmed by pathology .In this paper, 14 cases of complete data reported as follows.1 Clinical data HUS features are: suddenly Appear hemolytic anemia and rapid renal failure may be associated with central nervous system damage, gastrointestinal bleeding and hematological abnormalities, including red blood cell fragmentation, thrombocytopenia and intravascular coagulation in this group of 14 patients are in line with this feature. According to Kaplan’s classification, the group of 8 cases of heavy, light 6 cases.1.1 General information of 8 males and 6 females.The ratio of male to female was 1.3: 1; 2 to 3 years old, 9 cases of 1 to 7 years old. 8 to 14 years in 3 cases, the average age of 5.7 years The group accounted for 61.3% of preschool children, the onset season of 7 to 10 months were a total of 10. 1.2 symptoms and signs of prodromal symptoms in 12 cases, including respiratory tract infection in 5 cases, Gastrointestinal infection in 7 cases.1.2.1 general symptoms of pale face in 13 cases, 14 cases of fatigue, fever in 9 cases, 6 cases of yellow dye, gastrointestinal bleeding in 7 cases, skin and mucous membrane bleeding in 6 cases .1.2.2 urinary symptoms in 11 cases Hematuria, of which 7 cases of gross hematuria.All patients had proteinuria, 11 down urine protein (卌) .Hypertension 5