目的:探讨根据博洛尼亚标准诊断的卵巢低反应(POR)患者体外受精(IVF)/卵胞质内单精子注射(ICSI)临床妊娠结局的预测因子。方法:回顾性分析392名符合博洛尼亚标准的POR患者的临床资料。采用多因素逻辑回归分析法研究这些POR患者IVF/ICSI-ET的临床妊娠结局的预测因子。结果:女方年龄、移植胚胎数和促排卵方案是POR患者IVF临床妊娠结局的预测因子,其中女方年龄是最佳的预测因子。结论:随着女方年龄的增加,妊娠率会不断下降。因此,应该鼓励博洛尼亚标准POR患者积极接受IVF-ET助孕。生长激素、ICSI或辅助孵化均不能明显改善POR患者的IVF临床妊娠结局。 PURPOSE: To investigate the predictors of clinical pregnancy outcome of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) in patients with ovarian hypofunction (POR) diagnosed according to Bologna criteria. Methods: The clinical data of 392 POR patients who met the Bologna criteria were retrospectively analyzed. Predictors of clinical pregnancy outcomes for IVF / ICSI-ET in these POR patients were studied using multivariate logistic regression analysis. Results: The age of women, number of embryos transferred and ovulation induction were predictors of IVF clinical pregnancy outcomes in POR patients, of which women’s age was the best predictor. Conclusion: As the woman’s age increases, the pregnancy rate will continue to decline. Therefore, BORNIA-standard POR patients should be encouraged to actively receive IVF-ET pregnancy support. Growth hormone, ICSI, or assisted hatching did not significantly improve IVF clinical pregnancy outcomes in POR patients.