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Таликмин(1,2-亚甲基二羟基-3,9,10-三甲氧基-N-甲基卟吩)系从小唐松草(Thalictrumminus L.)根部分离的生物碱。本文报导它的镇咳、毒性和其他一些药理作用。(1)实验用异戊巴比妥钠麻醉猫16只和狗9只。用电刺激喉上神经和机械刺激气管引起咳嗽。从股静脉分别注入盐酸Таликмин和磷酸可待因溶液;(2)用麻醉猫和狗研究Таликмин对血压和呼吸的影响;静脉注射肾上腺素(10～20微克/公斤),根据血压和瞬膜紧张度变化判断Таликмин对外
Таликмин (1,2-methylenedihydroxy-3,9,10-trimethoxy-N-methylporphin) is an alkaloid isolated from the roots of Thalictrum minus L. This article reports its antitussive, toxic and other pharmacological effects. (1) Experimental anesthetized cats with pentobarbital sodium 16 dogs and 9 dogs. Electrical stimulation of the laryngeal nerve and mechanical stimulation of the trachea causes coughing. (2) anesthetized cats and dogs to study the effects of Таликмин on blood pressure and respiration; intravenous injection of epinephrine (10 to 20 μg / kg) according to blood pressure and instantaneous membrane tension Degree change judgment Таликмин external