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目的:了解北京地区2005年1~4月类流感样病例儿童流感嗜血杆菌感染的情况。方法:采集在北京儿童医院儿科门诊就诊病例,年龄1周~6岁,病程在3 d内的126名类流感样病例患儿的咽部分泌物,接种于巧克力平板上,分离培养。并采用卫星试验和X+V因子需求试验进行鉴定;应用SPSS11.5统计软件进行卡方检验。结果:共分离到23株流感嗜血杆菌,分离率为18.3%;男女儿童感染流感嗜血杆菌无显著性差异(P>0.05);并且多发生于2~6岁儿童;进入4月份以后,流感嗜血杆菌分离率为44.5%,明显高于此次调查的其它时段(P<0.01);23株流感嗜血杆菌其中共有5株与流感病毒合并感染。结论:流感嗜血杆菌是造成儿童急性呼吸道感染的主要病原之一。
Objective: To understand the situation of Haemophilus influenzae in children with influenza-like illness in Beijing from January to April in 2005. Methods: The pharyngeal secretions of 126 cases of influenza-like illness in children pediatric outpatient department of Beijing Children’s Hospital from 1 week to 6 years old within 3 days were collected and inoculated onto chocolate plates for isolation and culture. And use satellite test and X + V factor demand test to identify; use SPSS11.5 statistical software for chi-square test. Results: A total of 23 Haemophilus influenzae isolates were isolated with a separation rate of 18.3%. There was no significant difference in the number of Haemophilus influenzae between the male and female children (P> 0.05), and occurred mostly in children aged 2 to 6 years. After entering April, Haemophilus influenzae separation rate was 44.5%, significantly higher than the other period of this survey (P <0.01); 23 strains of Haemophilus influenzae, of which a total of 5 and influenza virus infection. Conclusion: Haemophilus influenzae is one of the major pathogens causing acute respiratory infection in children.