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目的研究采用布地奈德气雾剂(普米克气雾剂)同孟鲁司特联合治疗小儿哮喘的效果。方法 50例哮喘症患儿按照治疗方法不同分为实验组和参照组,各25例。所有患儿行常规性抗感染治疗等,同时参照组给予单一普米克气雾剂治疗,实验组则在参照组的基础之上联用孟鲁司特治疗。观察比较两组患儿的治疗效果。结果实验组患儿治疗总有效率为96%,明显高于参照组的76%,差异具有统计学意义(P<0.05)。实验组出现2例轻微心悸的患者,不良反应发生率为8%;参照组出现3例心悸患者,不良反应发生率为12%;两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论在临床当中,针对哮喘症患儿,行以孟鲁司特和普米克气雾剂联合的治疗方式,能够获得非常理想的治疗效果,值得临床应用。
Objective To investigate the efficacy of budesonide aerosol (pulmicort aerosol) combined with montelukast in the treatment of pediatric asthma. Methods 50 cases of asthmatic children were divided into experimental group and reference group according to the different treatment methods, each 25 cases. All children underwent routine anti-infective therapy, while the same reference group given a single Pulmicort aerosol treatment, the experimental group in the reference group based on the combination of montelukast treatment. Observed and compared the treatment effect of two groups of children. Results The total effective rate of treatment group was 96%, significantly higher than 76% of the reference group, the difference was statistically significant (P <0.05). There were 2 patients with mild palpitations in the experimental group, the incidence of adverse reactions was 8%; 3 patients with palpitations in the reference group, the incidence of adverse reactions was 12%; There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion In clinical practice, the combination of montelukast and Pulmicort aerosol treatment for children with asthma can achieve very satisfactory therapeutic effect and is worthy of clinical application.