对能够测定随意尿hCG的医疗单位,在测定hCG时若能知hCG量于妊娠早期开始增加的日内变动幅度及排出动态,指导定时采尿是重要的。Daniel等(1963年)报道尿中hCG浓度清晨高。检测时用尿hCG浓度高的清晨尿,用红细胞凝集抑制的半定量方法测定,但精确度及敏感度均有问题。 It is important for a medical unit that can measure free urinary hCG to guide timing urine collection if it knows the intra-day rate of change and excretion of hCG during the first trimester of pregnancy when measuring hCG. Daniel et al. (1963) reported urinary hCG concentrations early in the morning. Early morning urine with high urinary hCG concentration was tested by semi-quantitative method with inhibition of agglutination of erythrocytes, but the accuracy and the sensitivity were both problematic.