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目的研究螺旋霉素联合替硝唑局部治疗慢性牙周炎56例治疗效果。方法选择2009年3月至2012年3月我院门诊部接诊的慢性牙周炎患者112例。随机分为实验组和对照组,各56例。实验组采用螺旋霉素联合替硝唑对患者进行局部治疗,对照组采用替硝唑对患者进行局部治疗。比较2组临床疗效。结果实验组总有效率94.6%明显高于对照组的82.1%,差异有统计学意义(P<0.05)。结论采用螺旋霉素联合替硝唑对慢性牙周炎患者进行局部给药治疗,效果良好,明显优于单纯使用替硝唑的临床疗效。
Objective To study the effect of spiramycin plus tinidazole in the treatment of 56 cases of chronic periodontitis. Methods From March 2009 to March 2012, 112 cases of chronic periodontitis were admitted to outpatient department of our hospital. Randomly divided into experimental group and control group, 56 cases each. Patients in the experimental group were treated locally with spiramycin plus tinidazole, and patients in the control group were treated with tinidazole topically. The clinical efficacy of two groups were compared. Results The total effective rate was 94.6% in the experimental group was significantly higher than 82.1% in the control group, the difference was statistically significant (P <0.05). Conclusion Spiramycin combined with tinidazole for chronic periodontitis in patients with local administration, the effect is good, significantly better than the clinical efficacy of tinidazole alone.