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设计了一种化学发光免疫分析试剂吖啶酯的合成新路线，以二苯胺为原料合成吖啶－９－羧酸，经酰氯化后与３－（４－羟基苯基）－丙酸－Ｎ－羟基琥珀酰亚胺酯反应得４－（２－琥珀酰亚胺基氧羰基乙基）苯基－９－吖啶羧酸酯，最后与氟磺酸甲酯反应即得４－（２－琥珀酰亚胺基氧羰基）苯基－１０－甲基吖啶－９－羧酸酯氟磺酸盐（俗称吖啶酯）
A new route for the synthesis of acridinium esters, a chemiluminescent immunoassay reagent, was designed. Acridine-9-carboxylic acid was synthesized from diphenylamine and reacted with 3- (4-hydroxyphenyl) propionic acid-N -hydroxysuccinimide ester to obtain 4- (2-succinimidyl oxycarbonylethyl) phenyl-9-acridine carboxylate and finally reacting with methyl fluorosulfonate to obtain 4- (2- Succinimidyl oxycarbonyl) phenyl-10-methylacridine-9-carboxylate fluorosulfonate (commonly known as acridinium ester)