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目的 探讨影响急性心肌梗塞（ＡＭ Ｉ）溶栓再灌注后临床疗效的相关因素。方法 ３９４ 例ＡＭ Ｉ患者均在尿激酶天普洛欣（ＵＫＴＰ）溶栓治疗梗塞相关血管（ＩＲＡ）再通后第７ 日采用９９ｍ ＴＣ－Ｍ ＩＢＩ心肌灌注显像（ＳＰＥＣＴ）检测心肌缺血面积（ＩＭ Ａ）。将可能影响ＩＭ Ａ 的 １０ 种因素分别进行相关分析。结果 ＩＭ Ａ 分别与发病至溶栓时间、发病年龄、溶栓前心律失常和左心衰竭、梗塞面积、ＵＫＴＰ剂量及溶栓开始至再通时间呈显著相关关系（Ｐ＜ ０．０５ 或 ０．０１）。与高血压、糖尿病、高脂血症无相关关系（Ｐ 均＞ ０．０５）。结论 溶栓治疗ＡＭ ＩＩＲＡ 再通后 ＩＭ Ａ 受多种因素影响，采取针对性控制措施对提高ＡＭ Ｉ的临床疗效有重要价值。
Objective To investigate the influencing factors of clinical efficacy after acute myocardial infarction (AMI) thrombolytic reperfusion. Methods Thirty-nine AMI patients underwent 99m TC-M IBI myocardial perfusion imaging (SPECT) on the 7th day after urokinase-thrombolysis (UKTP) thrombectomy-related infarction-related blood vessel (IRA) (IM A). Ten factors that may affect IM A were analyzed separately. Results IM A was significantly correlated with onset of thrombolysis, age of onset, arrhythmia before thrombolysis and left ventricular failure, infarct size, dose of UKTP and time from initiation of thrombolysis to reperfusion (P <0.05 or P <0.05). 01). And hypertension, diabetes, hyperlipidemia no correlation (P> 0.05). Conclusion IM A is influenced by many factors after AM IIRA recanalization by thrombolytic therapy. It is of great value to take targeted control measures to improve the clinical efficacy of AMI.