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目的 :观察金双歧 (长双歧杆菌制剂 )对肠易激综合征 (irritablebowel syndrome,IBS)的治疗效果。方法 :顺序随机取本院门诊按“罗马标准 I”的诊断标准确诊为 IBS患者 14 2例入组 ,接受金双歧治疗 ,所有病人均排除器质性疾病。IBS患者口服金双歧 2 .0 g,2次 /d,2周为一疗程。观察期间记录治疗前及治疗后每一天的包括腹痛、腹胀、排便频率、排便异常和大便性状的病状积分和不良反应。结果 :治疗 1~ 2周后的总体征候和单项症状积分均有明显改善 ,总体征候显效率分别达 2 4.6%~ 40 .8% ,总有效率分别达65 .4%~ 85 .2 % ,无一例发生不良反应。结论 :长双歧杆菌制剂治疗 IBS疗效确切、病人依从好 ,值得推广应用。
Objective: To observe the therapeutic effect of bifidobacterium longum (Bifidobacterium longum) on irritable bowel syndrome (IBS). Methods: The patients randomly selected from our hospital according to the diagnostic criteria of “Rome Standard I” were enrolled in the study. Forty-two patients with IBS were enrolled in this study. All patients were excluded organic disease. Patients with IBS oral gold bifidobacterium 2. 0 g, 2 times / d, 2 weeks for a course of treatment. During the observation period, points and adverse reactions including abdominal pain, abdominal distension, defecation frequency, defecation abnormalities and stool traits were recorded before and after treatment. Results: After 1 to 2 weeks of treatment, the overall symptom scores and individual symptom scores were significantly improved. The overall signs markedly effective rate was respectively 2.46% ~ 40.8%, the total effective rate was 65.4% ~ 85.2%, respectively. No case of adverse reactions. Conclusion: The treatment of IBS with Bifidobacterium longum is effective and reliable. It is worth popularizing and applying.