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原发性甲状旁腺机能亢进症(PHPT)是一种罕见的内分泌代谢疾病,该病早期症状隐匿,晚期复杂多变,临床很易误诊、漏诊。据文献报导误诊率达72%,总结广西医科大学一附院1985~1996年12年间收治的PHPT患者5例,均有不同程度的误诊。本文分析了该病的误诊、误治原因,认为通过以下几点可避免误诊:①提高对该病的认识。②血钙普查或门诊常规查血钙有助于早期诊断。③血清I—PTH、T—PTH及PTH—rP的检测有助于确诊。④TC99m—MIBI核素扫描有助于定位诊断。
Primary hyperparathyroidism (PHPT) is a rare endocrine and metabolic diseases, the early symptoms of the disease concealed, the late complex and volatile, clinical misdiagnosis, missed diagnosis. According to reports of misdiagnosis rate of 72%, summarize the First Affiliated Hospital of Guangxi Medical University from 1985 to 1996, 12 cases of PHPT patients were treated in 5 cases, all have varying degrees of misdiagnosis. This article analyzes the misdiagnosis, misdiagnosis of the disease, that the following points to avoid misdiagnosis: ① improve the understanding of the disease. ② blood calcium screening or outpatient routine check calcium help early diagnosis. ③ serum I-PTH, T-PTH and PTH-rP test will help confirm the diagnosis. ④TC99m-MIBI radionuclide scan can help locate the diagnosis.