【摘 要】
：
Dear Editor,rnThe highly conserved neuropeptides arginine vasopressin(AVP)and oxytocin(OT)signal through a family of Class A G protein-coupled receptors(GPCRs),the AVP receptors V1aR,V1bR and V2R and the OT receptor OXTR.1,2 V2R is predominantly found in
【机 构】
：
Kobilka Institute of Innovative Drug Discovery,School of Life and Health Sciences,Chinese University
论文部分内容阅读
Dear Editor,rnThe highly conserved neuropeptides arginine vasopressin(AVP)and oxytocin(OT)signal through a family of Class A G protein-coupled receptors(GPCRs),the AVP receptors V1aR,V1bR and V2R and the OT receptor OXTR.1,2 V2R is predominantly found in the kidney and plays a critical role in body fluid homeostasis.2 Among all AVP and OT receptors,V2R is the only one that activates the heterotrimeric Gs family to induce cAMP accumulation(Supple-mentary information,Fig.S1).
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