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本文用垂体后叶素和hCRH对正常人(5例)、库欣病(12例)、肾上腺腺瘤(4例)做联合的CRH试验,结果在正常人ACTH与血皮质醇均显著增加(P<0.01)。在所有12例增生病人中,ACTH与血F均在已增高的基础值上进一步升高(P值均<0.01),未见假阴性结果。而4例腺瘤病人,联合试验使血浆ACTH稍有升高,而血F不增高。在比较增生与腺瘤病人的ACTH与血F峰值与基值差的绝对值(△)时,发现增生病人△ACTH>20pg/ml,△F>7μg/ml;反之则为腺瘤。
In this paper, the combined CRH test of pituitrin and hCRH in normal subjects (5 cases), Cushing’s disease (12 cases) and adrenal adenoma (4 cases) was performed. The results showed that ACTH and cortisol were significantly increased in normal subjects P <0.01). In all 12 patients with hyperproliferation, both ACTH and F increased further on the increased basal values (P <0.01), with no false-negative results. The 4 cases of adenoma, the joint test slightly elevated plasma ACTH, while the blood F is not increased. In comparing hyperplasia and adenoma patients with ACTH and blood F peak value and the absolute value of the difference (△) found hyperplasia △ ACTH 20pg / ml, △ F> 7μg / ml; otherwise adenoma.