闭塞性细支气管炎（Bronchiolitisobrians，BO）临床少见，是一种发生于小气道的纤维化肺疾病，对激素反应差，预后不良。l一般资料本病于19OI年首先由Large报道’“，患者多有肺部感染史，毒气吸入史，结缔组织病史或器官移植术史。据报道”‘，约13％的骨髓移植者可并发此病 Bronchiolitisobrians (BO), a rare clinical form, is a fibrotic lung disease that develops in the small airways and has poor response to hormones and poor prognosis. l General information The disease was first reported by the Large in 1910, and most patients had a history of pulmonary infection, history of toxic gas inhalation, history of connective tissue, or organ transplant. "About 13% of all bone marrow transplants can be complicated This disease