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本文最初发表于2015年《Leukemia》杂志上,文章题录为Yan H,Wu QL,Sun CY,et al.piRNA-823contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma[J].Leukemia,2015,29:196-206。本文是研究多发性骨髓瘤发病机制的优秀文章代表,在国内外范围内首次发现了piRNA-823对多发性骨髓瘤细胞DNA甲基化和血管生成的促进作用,为骨髓瘤的研究提供了新的思路。经通信作者许可,通过此佳文解读的方式来推动骨髓瘤基础研究领域新方向的进展。
This article was originally published in the 2015 issue of Leukemia, titled Yan H, Wu QL, Sun CY, et al., PRNA-823 contributions to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma [J] 2015,29: 196-206. This article is an excellent article on behalf of the pathogenesis of multiple myeloma representatives, for the first time at home and abroad found piRNA-823 on multiple myeloma cells DNA methylation and angiogenesis promoting role for the study of myeloma provided a new Train of thought. Approved by the author of this communication, this paper will promote the progress in the new direction of basic research in myeloma cells.