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[目的]通过试验优选小儿消食颗粒中有效成分厚朴酚、和厚朴酚的提取工艺。[方法]采用正交试验法,以提取时间、加水量和提取次数为研究考察的主要影响因素,每个因数选取3个水平进行实验设计,以厚朴酚、和厚朴酚的含量为指标进行考察。[结果与结论]影响小儿消食颗粒中有效成分厚朴酚、和厚朴酚的提取工艺的因素为提取溶液的用量、提取次数和提取时间,即8倍90%乙醇提取2次,每次1.5h,为该制剂的最佳生产工艺。
[Objective] The research aimed to optimize the extraction process of honokiol and honokiol from the active ingredient Xiaoya Xiaoshi granules. [Method] The orthogonal experiment method was used to extract the time, the amount of water and the number of extraction as the main influencing factors. Three factors were selected for the experimental design. The contents of honokiol and honokiol were taken as indexes To inspect. [Results and Conclusions] The factors influencing the extraction process of honokiol and honokiol in Xiaoer Xiaoye Granules are the amount of extraction solution, the number of extraction and the extraction time, that is, 8 times 90% ethanol extraction twice h, the preparation of the best production process.