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目的研究重型乙型肝炎患者继发性感染的临床特点。方法回顾性分析医院感染内科收治的70例重型乙型肝炎患者继发性感染的临床特点。结果70例患者中发生继发感染者60例(85.7%),其中34例出现2个以上部位感染。较常见的感染部位为腹腔、肺部和胆道,感染率分别为47.1%、35.7%和28.6%,其他感染部位有泌尿道、口腔、上呼吸道、肠道、败血症,感染率分别为8.6%、7.1%、5.7%、2.9%和2.9%,真菌感染12例,占所有感染的17.1%。继发感染患者体温可表现为高热、低热或体温正常,外周血白细胞和中性粒细胞比率可增高或正常。结论重型乙型肝炎患者发生继发性感染比率高,临床表现复杂。
Objective To study the clinical features of secondary infection in patients with severe hepatitis B. Methods The clinical features of secondary infection in 70 patients with severe hepatitis B admitted to hospital for nosocomial infection were analyzed retrospectively. Results Sixty cases (85.7%) of the 70 patients were found to have secondary infection, of which 34 cases had more than two infections. The more common sites of infection were abdominal cavity, lung and biliary tract, the infection rates were 47.1%, 35.7% and 28.6% respectively. Other infected sites were urinary tract, oral cavity, upper respiratory tract, intestinal tract and sepsis. The infection rates were 8.6% 7.1%, 5.7%, 2.9% and 2.9%, 12 fungal infections, accounting for 17.1% of all infections. Secondary infection in patients with body temperature can be manifested as high fever, fever or normal body temperature, peripheral white blood cell and neutrophil ratio can be increased or normal. Conclusion The incidence of secondary infection in patients with severe hepatitis B is high and the clinical manifestations are complex.