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目的探讨分析雷公藤多甙联合米非司酮对子宫肌瘤剔除术后患者康复的影响。方法将该院2015年2月—2016年10月接收的96例子宫肌瘤患者作为研究对象,将患者随机分为对照组和研究组,两组均为48例,对照组术后采用常规处理,研究组在对照组的基础上采用雷公藤多甙联合米非司酮口服治疗,比较两组患者术前及术后3、6个月雌二醇、孕酮水平及子宫肌瘤复发率及主观症状出现情况。结果两组患者术前雌二醇、孕酮水平比较差异无统计学意义(P>0.05);术后3、6个月研究组患者的雌二醇、孕酮水平均显著低于对照组,差异有统计学意义(P<0.05);研究组患者的子宫肌瘤复发率和主观症状出现率分别为2.08%、16.67%,对照组患者的子宫肌瘤复发率和主观症状出现率分别为8.33%、41.67%。研究组患者的子宫肌瘤复发率及主观症状出现率均明显低于对照组,差异有统计学意义(P<0.05)。结论雷公藤多甙联合米非司酮能有效促进子宫肌瘤剔除术后患者康复,值得在临床上廊用推广。
Objective To investigate the effect of Tripterygium wilfordii polyespide combined with mifepristone on the rehabilitation of patients with myomectomy. Methods A total of 96 patients with uterine leiomyoma received from February 2015 to October 2016 in our hospital were randomly divided into control group and study group, 48 cases in both groups. The control group received routine treatment , The study group in the control group based on the use of tripterygium glycosides combined with mifepristone oral treatment, two groups of patients before and after 3,6 months of estradiol, progesterone levels and uterine fibroids recurrence rate and Subjective symptoms appear. Results There was no significant difference in preoperative estradiol and progesterone levels between the two groups (P> 0.05). The levels of estradiol and progesterone in the study group at 3 and 6 months after operation were significantly lower than those in the control group (P <0.05). The recurrence rate and subjective symptom of uterine fibroids in study group were 2.08% and 16.67%, respectively. The recurrence rate and subjective symptom of uterine fibroids in the control group were 8.33 %, 41.67%. The recurrence rate of the uterine fibroids and the subjective symptoms in the study group were significantly lower than those in the control group (P <0.05). Conclusion Tripterygium glycosides combined with mifepristone can effectively promote the recovery of patients with myomectomy, it is worth clinical promotion.